The Eurofever project was promoted in 2008 by the work group of autoinflammatory diseases of the Paediatric Rheumatology European Society (PRES) and was supported by the Executive Agency for Health and Consumers (EAHC). 
The general aims of the Eurofever project are to: 
· sensitive pediatricians and pediatric rheumatologists to the prompt recognition of Autoinflammatory Diseases; 
· provide proper information to families affected by these conditions; 
· increase the knowledge on the clinical presentation, response to treatment and complications of theses rare disorders. 

The main objective of the project has been the creation of a registry of autoinflammatory diseases. 
Last year a new section dedicated to Efficacy and Safety has been implemented and the registry is now able to collect also longitudinal information. 
New auto - inflammatory diseases have been added, as of today the following conditions are considered by the Project: 

· Behçet disease
· Blau’s syndrome/Early onset sarcoidosis
· Cryopyrin associated periodic syndrome
· Chronic recurrent multifocal osteomyelitis
· Deficiency of IL-1 receptor antagonist
· Familial Mediterrean Fever
· Mevalonate kinase deficency (Hyper IgD syndrome)
· NLRP12 -associated periodic syndrome
· Pyogenic Sterile Arthritis, Pyoderma Gangrenosum and Acne (PAPA) syndrome
· Tumor necrosis factor receptor-associated periodic syndrome (TRAPS)
· Periodic fever, aphthous stomatitis, pharyngitis and cervical adenitis (PFAPA)
· CANDLE syndrome
· DITRA syndrome
· Schnitzler syndrome
· Majeed syndrome
· Deficiency of Adenosine Deaminase 2 (DADA2)
· STING-asociated vasculopathy with onset in infancy (SAVI)
· CARD14 mediated psoriasis (CAMPS)
· Undefined Periodic fever